Stop all running Biztalk services, load up SQL Management Studio, on the BiztalkDTADb database run the following script. Note that this script does not archive data.
declare @dtLastBackup datetime set @dtLastBackup = GetUTCDate() exec dtasp_PurgeTrackingDatabase 1, 0, 1, @dtLastBackup
After this has completed you can shrink the database files.
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